Article
trans-acting proteins involved in RNA encapsidation and viral assembly in human immunodeficiency virus type 1.
Journal of virology - 1 Feb 1996
Kaye J F, Lever A M
Abstract excerpt
The human immunodeficiency virus type 1 gag gene product Pr55gag self-assembles when expressed on its own in a variety of eukaryotic systems. Assembly in T lymphocytes has not previously been studied, nor is it clear whether Pr55gag particles can package genomic RNA or if the Gag-Pol polyprotein is required. We have used a series of constructs that express Gag or Gag-Pol proteins with or without the viral...
Topics
- Amino Acid Sequence
- Animals
- Binding Sites
- Cell Line
- Gene Products, gag
- Gene Products, pol
- Genes, gag
- HIV-1
- Humans
- Molecular Sequence Data
- Mutation
- Protein Precursors