P40SDB25, a putative CDK inhibitor, has a role in the M/G1 transition in Saccharomyces cerevisiae.

doi:10.1101/gad.8.14.1640

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Article

P40SDB25, a putative CDK inhibitor, has a role in the M/G1 transition in Saccharomyces cerevisiae.

Genes & development - 15 Jul 1994

Donovan J D, Toyn J H, Johnson A L, Johnston L H

Abstract excerpt

The Saccharomyces cerevisiae protein kinase Dbf2 carries out an essential function in late mitosis, and its kinase activity is cell-cycle regulated around anaphase/telophase. We have isolated SDB25, a high copy suppressor of temperature-sensitive dbf2 mutants, and genetic analysis suggests that the two proteins may function in parallel pathways in late mitosis. SDB25 encodes p40, a previously characterized...

Topics

Amino Acid Sequence
Base Sequence
Blotting, Northern
Blotting, Southern
CDC28 Protein Kinase, S cerevisiae
Cell Cycle
Cyclin-Dependent Kinase Inhibitor Proteins
DNA, Fungal
Fungal Proteins
G1 Phase
Gene Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression Regulation, Fungal

Genes, Fungal

Genes, Suppressor

Genotype

Mitosis

Molecular Sequence Data

Phenotype

Source

Open in PubMed

Identifiers

PMID: 7958845
DOI: 10.1101/gad.8.14.1640

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7958845-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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