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Article

Stoichiometry of recombinant N-methyl-D-aspartate receptor channels inferred from single-channel current patterns.

The Journal of general physiology - 1 Nov 1997

Premkumar L S, Auerbach A

Abstract excerpt

Single-channel currents were recorded from mouse NR1-NR2B (zeta-epsilon2) receptors containing mixtures of wild-type and mutant subunits expressed in Xenopus oocytes. Mutant subunits had an asparagine-to-glutamine (N-to-Q) mutation at the N0 site of the M2 segment (NR1:598, NR2B:589). Receptors with pure N or Q NR1 and NR2 subunits generated single-channel currents with distinctive current patterns. Based on main...

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Identifiers

PMID: 9348322
DOI: 10.1085/jgp.110.5.485
PMCID: PMC2229386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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