Article
Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors.
Proceedings. Biological sciences - 22 Nov 1995
Béhé P, Stern P, Wyllie D J, Nassar M, Schoepfer R, Colquhoun D
Abstract excerpt
Co-expression of wild-type and mutated NMDA NR1 (N598R) subunits in Xenopus oocytes has been used to determine the stoichiometry of the NMDA receptor-channel. When expressed together, wild-type NR2A and mutant NR1 (N598R) subunits produced channels with a main conductance of 2.6 pS and a sublevel of 1.2 pS. These conductances were clearly different from those obtained from wild-type NR1 and wild-type NR2A...
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