Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Formation of NR1/NR2 and NR1/NR3 heterodimers constitutes the initial step in N-methyl-D-aspartate receptor assembly.

The Journal of biological chemistry - 4 Jan 2008

Schüler Thomas, Mesic Ivana, Madry Christian, Bartholomäus Ingo, Laube Bodo

Abstract excerpt

N-Methyl-D-aspartate (NMDA) receptors are tetrameric protein complexes composed of the glycine-binding NR1 subunit with a glutamate-binding NR2 and/or glycine-binding NR3 subunit. Tri-heteromeric receptors containing NR1, NR2, and NR3 subunits reconstitute channels, which differ strikingly in many properties from the respective glycine- and glutamate-gated NR1/NR2 complexes and the NR1/NR3 receptors gated by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dimerization
Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electrophysiology

Share to Fluorescence Resonance Energy Transfer

Share to Oocytes

Share to Protein Subunits

Share to Receptors, N-Methyl-D-Aspartate

Share to Xenopus laevis

Source

Identifiers

PMID: 17959602
DOI: 10.1074/jbc.M703539200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Formation of NR1/NR2 and NR1/NR3 heterodimers constitutes the initial step in N-methyl-D-aspartate receptor assembly.PMID 17959602Read ↗

Role of the fourth membrane domain of the NR2B subunit in the assembly of the NMDA receptor.Semantic proximity Read ↗

Masking of the endoplasmic reticulum retention signals during assembly of the NMDA receptor.Semantic proximity Read ↗

Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits.Semantic proximity Read ↗

Supralinear potentiation of NR1/NR3A excitatory glycine receptors by Zn2+ and NR1 antagonist.Semantic proximity Read ↗

Two regions in the N-terminal domain of ionotropic glutamate receptor 3 form the subunit oligomerization interfaces that control subtype-specific receptor assembly.Semantic proximity Read ↗

Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-D-aspartate receptor population in adult hippocampal synapses.Semantic proximity Read ↗

Assembly of GABA(A) receptors (Review).Semantic proximity Read ↗

Stoichiometry of recombinant N-methyl-D-aspartate receptor channels inferred from single-channel current patterns.Semantic proximity Read ↗

Dual Role of NMDAR Containing NR2A and NR2B Subunits in Alzheimer’s DiseaseSemantic proximity Read ↗

[Construction of expression vectors for C-terminally deleted NR2B subunit mutants and their application in the study of assembling of NMDA receptors].Semantic proximity Read ↗

Specific Roles of NMDA Receptor Subunits in Mental Disorders.Semantic proximity Read ↗

Subunit-specific NMDA receptor trafficking to synapses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.