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Article

DNA replication and order of cell cycle events: a role for protein isoprenylation?

Biological chemistry - 1 Sept 1997

Galli I, Uchiyama M, Wang T S

Abstract excerpt

When the aya1+ gene is mutated, Schizosaccharomyces pombe cells become unable to react appropriately to a delay in DNA replication. Instead of stalling the cell cycle to allow completion of DNA synthesis, they proceed unperturbed towards mitosis and attempt to segregate the still unreplicated chromosomes. As a result, the genetic material segregates unevenly and the nuclei assume a mitotic catastrophe phenotype,...

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Identifiers

PMID: 9348105
DOI: 10.1515/bchm.1997.378.9.963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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