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Article

Fission yeast Sap1 protein is essential for chromosome stability.

Eukaryotic cell - 1 Oct 2003

de Lahondès Raynald, Ribes Veronique, Arcangioli Benoit

Abstract excerpt

Sap1 is a dimeric sequence-specific DNA binding-protein, initially identified for its role in mating-type switching of the fission yeast Schizosaccharomyces pombe. The protein is relatively abundant, around 10,000 dimers/cell, and is localized in the nucleus. sap1+ is essential for viability, and transient overexpression is accompanied by rapid cell death, without an apparent checkpoint response and independently...

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Identifiers

PMID: 14555473
DOI: 10.1128/EC.2.5.910-921.2003
PMCID: PMC219360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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