Article
The nuclear actin-related protein Act3p/Arp4 influences yeast cell shape and bulk chromatin organization.
Journal of cellular biochemistry - 1 May 2008
Georgieva Milena, Harata Masahiko, Miloshev George
Abstract excerpt
ACT3/ARP4 is an essential gene, coding for the actin-related protein Act3p/Arp4 of Saccharomyces cerevisiae located within the nucleus. Act3p/Arp4 is a stoichiometric component of the NuA4, INO80, and SWR1 chromatin modulating complexes, and recruits these complexes onto chromatin for their proper chromatin functions. Mutated Act3p/Arp4 leads to impairment of the functions of these complexes and affects...
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