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Article

Detection of gene-environment interactions in joint segregation and linkage analysis.

American journal of human genetics - 1 Nov 1997

Gauderman W J, Faucett C L

Abstract excerpt

We compare approaches for analysis of gene-environment (G x E) interaction, using segregation and joint segregation and linkage analyses of a quantitative trait. Analyses of triglyceride levels in a single large pedigree demonstrate the two methods and show evidence for a significant interaction (P=.015 when segregation analysis is used; P=.006 when joint analysis is used) between a codominant major gene and...

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Identifiers

PMID: 9345092
DOI: 10.1086/301597
PMCID: PMC1716048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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