Article
A mutation in integrase can compensate for mutations in the simian immunodeficiency virus att site.
Journal of virology - 1 Nov 1997
Du Z, Ilyinskii P O, Lally K, Desrosiers R C, Engelman A
Abstract excerpt
Sequences at the left terminus of U3 in the left long terminal repeat (LTR) and at the right terminus of U5 in the right LTR are important for integration of retroviral DNA. In the infectious pathogenic molecular clone of simian immunodeficiency virus strain mac239 (SIVmac239), 10 of the 12 terminal base pairs form an imperfect inverted repeat structure (5' TGGAAGGGATTT 3' [nucleotides 1 to 12] and 3'...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
