Article
An intact U5-leader stem is important for efficient replication of simian immunodeficiency virus.
Journal of virology - 1 Dec 2001
Guan Y, Diallo K, Whitney J B, Liang C, Wainberg M A
Abstract excerpt
Previous work has shown that four deletions in simian immunodeficiency virus (SIV), termed SD1a, SD1b, SD1c, and SD6, which eliminated sequences at nucleotide positions 322 to 362, 322 to 370, 322 to 379, and 371 to 379, respectively, located downstream of the primer binding site, impaired viral replication capacity to different extents. Long-term culturing of viruses containing the SD1a, SD1b, and SD6 deletions...
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