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Article

Leader sequences downstream of the primer binding site are important for efficient replication of simian immunodeficiency virus.

Journal of virology - 1 Oct 2000

Guan Y, Whitney J B, Diallo K, Wainberg M A

Abstract excerpt

Simian immunodeficiency virus (SIV) infection of macaques is remarkably similar to that of human immunodeficiency virus type 1 (HIV-1) in humans, and the SIV-macaque system is a good model for AIDS research. We have constructed an SIV proviral DNA clone that is deleted of 97 nucleotides (nt), i.e., construct SD, at positions (+322 to +418) immediately downstream of the primer binding site (PBS) of SIVmac239. When...

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Identifiers

PMID: 10982327
DOI: 10.1128/jvi.74.19.8854-8860.2000
PMCID: PMC102079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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