Article
Differential regulation of transcription of p21 and cyclin D1 conferred by TAF(II)250.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Oct 1997
Rushton J J, Steinman R A, Robbins P D
Abstract excerpt
The TATA-binding protein-associated factor TAF(II)250, the largest subunit of TFIID, was first identified as the cell cycle regulatory protein CCG1. The ts13 Syrian hamster ovary fibroblast cell line, which contains a temperature-sensitive point mutation in TAF(II)250/CCG1, is arrested in G1 following a shift to the nonpermissive temperature. Here we demonstrate that the level of the D-type cyclins, in particular...
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