Article
TAFII250-dependent transcription of cyclin A is directed by ATF activator proteins.
Genes & development - 15 Oct 1997
Wang E H, Zou S, Tjian R
Abstract excerpt
A specific mutation in TAFII250, the largest subunit of the transcription factor TFIID, disrupts cell growth control in the temperature-sensitive mutant hamster cell line ts13. Transcription from the cyclin A and D1 but not the c-fos and myc promoters is also dramatically reduced in ts13 cells at...
Topics
- Animals
- Cell Line
- Cricetinae
- Cyclin A
- Cyclin D1
- DNA-Binding Proteins
- Enhancer Elements, Genetic
- Genes, fos
- Genes, myc
- HeLa Cells
- Histone Acetyltransferases
- Humans
- Luciferases
- Mutagenesis, Site-Directed
- Mutation
- Nuclear Proteins
- Promoter Regions, Genetic
- Recombinant Fusion Proteins
