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Article

p53 Transcriptional Activation Mediated by Coactivators TAF <sub>II</sub> 40 and TAF <sub>II</sub> 60

6 Jan 1995

Abstract excerpt

The tumor suppressor protein p53 is a transcriptional regulator that enhances the expression of proteins that control cellular proliferation. The multisubunit transcription factor IID (TFIID) is thought to be a primary target for site-specific activators of transcription. Here, a direct interaction between the activation domain of p53 and two subunits of the TFIID complex, TAFII40 and TAFII60, is reported. A...

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PMID: 7809597
DOI: 10.1126/science.7809597

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p53 Transcriptional Activation Mediated by Coactivators TAF <sub>II</sub> 40 and TAF <sub>II</sub> 60PMID 7809597Read ↗

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TAF(II)s mediate activation of transcription in the Drosophila embryo.Semantic proximity Read ↗

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