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Article

TAF1 histone acetyltransferase activity in Sp1 activation of the cyclin D1 promoter.

Molecular and cellular biology - 1 May 2005

Hilton Traci L, Li Yun, Dunphy Elizabeth L, Wang Edith H

Abstract excerpt

A missense mutation within the histone acetyltransferase (HAT) domain of the TATA binding protein-associated factor TAF1 induces ts13 cells to undergo a late G(1) arrest and decreases cyclin D1 transcription. We have found that TAF1 mutants (Delta844-850 and Delta848-850, from which amino acids 844 through 850 and 848 through 850 have been deleted, respectively) deficient in HAT activity are unable to complement...

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Share to Acetylation
Share to Acetyltransferases
Share to Cyclin D1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone Acetyltransferases

Share to Response Elements

Share to Sp1 Transcription Factor

Share to TATA-Binding Protein Associated Factors

Share to Transcription Factor TFIID

Source

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Identifiers

PMID: 15870300
DOI: 10.1128/MCB.25.10.4321-4332.2005
PMCID: PMC1087727

Genes

TAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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