Article
The Drosophila gene morula inhibits mitotic functions in the endo cell cycle and the mitotic cell cycle.
Development (Cambridge, England) - 1 Sept 1997
Reed B H, Orr-Weaver T L
Abstract excerpt
In the endo cell cycle, rounds of DNA replication occur in the absence of mitosis, giving rise to polyploid or polytene cells. We show that the Drosophila morula gene is essential to maintain the absence of mitosis during the endo cycle. During oogenesis in wild-type Drosophila, nurse cells become polyploid and do not contain cyclin B protein. Nurse cells in female-sterile alleles of morula begin to become...
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