Article
Terno, a cyclin-interacting protein regulating meiotic exit and sperm differentiation in Drosophila.
The Journal of cell biology - 5 Oct 2026
Bucciarelli Elisabetta, Graziadio Lucia, Pellacani Claudia, Somma Maria Patrizia, Mencarelli Caterina, Bonaccorsi Silvia, Gatti Maurizio
Abstract excerpt
In animal systems, the only case of third meiotic division without a prior round of DNA replication has been described in Drosophila males carrying mutations in roughex, a gene encoding an inhibitor of Cdk1 activity. Here, we describe another Drosophila gene, terno (teo), that regulates meiotic exit in males. In teo mutants, meiosis I and II are regular, but in many germline cysts, the 64 haploid spermatids...
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