Article
The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completion.
Genes & development - 1 Oct 1996
Lilly M A, Spradling A C
Abstract excerpt
Early during Drosophila oogenesis the 16 interconnected cells of each germ-line cyst choose between two alternative fates. The single future oocyte enters meiosis, arrests, and becomes transcriptionally quiescent. The remaining 15 cells initiate a series of polyploid cell cycles to prepare for th...
Topics
- Animals
- Cell Cycle
- Cell Nucleus
- Cyclins
- DNA Replication
- DNA, Ribosomal
- DNA, Satellite
- Drosophila
- Embryo, Nonmammalian
- Female
- Gene Expression Regulation, Developmental
- Heterochromatin
- Mutation
- Oocytes
- Oogenesis
- Ovary
- Polyploidy
- Reproduction