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Article

The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completion.

Genes & development - 1 Oct 1996

Lilly M A, Spradling A C

Abstract excerpt

Early during Drosophila oogenesis the 16 interconnected cells of each germ-line cyst choose between two alternative fates. The single future oocyte enters meiosis, arrests, and becomes transcriptionally quiescent. The remaining 15 cells initiate a series of polyploid cell cycles to prepare for their role as nurse cells. Like many other polyploid and polytene cells, during nurse cell growth the major satellite...

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Identifiers

PMID: 8843202
DOI: 10.1101/gad.10.19.2514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completion.PMID 8843202Read ↗

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