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Article

The E2F cell cycle regulator is required for Drosophila nurse cell DNA replication and apoptosis.

Mechanisms of development - 1 Dec 2002

Royzman Irena, Hayashi-Hagihara Aki, Dej Kimberley J, Bosco Giovanni, Lee Janice Y, Orr-Weaver Terry L

Abstract excerpt

During Drosophila oogenesis nurse cells become polyploid, enabling them to provide the developing oocyte with vast amounts of maternal messages and products. The nurse cells then die by apoptosis. In nurse cells, as in many other polyploid or polytene tissues, replication is differentially contro...

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PMID: 12464435
DOI: 10.1016/s0925-4773(02)00388-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12464435-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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