The MCM16 gene of the yeast Saccharomyces cerevisiae is required for chromosome segregation.

doi:10.1007/s004380050892

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Article

The MCM16 gene of the yeast Saccharomyces cerevisiae is required for chromosome segregation.

Molecular & general genetics : MGG - 1 Nov 1998

Sanyal K, Ghosh S K, Sinha P

Abstract excerpt

We have cloned and characterized the MCM16 gene required for the maintenance of minichromosomes in the yeast Saccharomyces cerevisiae. This gene corresponds to a 181-amino acid ORF, YPR046W, on chromosome XVI. Mutant cells carrying minichromosomes accumulate them in higher copy numbers than do wi...

Topics

Chromosome Deletion
Chromosome Segregation
Cloning, Molecular
DNA-Binding Proteins
Fungal Proteins
Kinetochores
Microtubules
Mutation
Phenotype
Plasmids
Recombinant Proteins
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Transcription, Genetic
beta-Galactosidase

Source

Open in PubMed

Identifiers

PMID: 9862478
DOI: 10.1007/s004380050892

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9862478-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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