Article
The MCM16 gene of the yeast Saccharomyces cerevisiae is required for chromosome segregation.
Molecular & general genetics : MGG - 1 Nov 1998
Sanyal K, Ghosh S K, Sinha P
Abstract excerpt
We have cloned and characterized the MCM16 gene required for the maintenance of minichromosomes in the yeast Saccharomyces cerevisiae. This gene corresponds to a 181-amino acid ORF, YPR046W, on chromosome XVI. Mutant cells carrying minichromosomes accumulate them in higher copy numbers than do wild-type cells. Intact dicentric plasmid could be recovered from the mutant, in contrast to the wild-type, in which the...
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