The mcm2 mutation of yeast affects replication, rather than segregation or amplification of the two micron plasmid.

doi:10.1016/0022-2836(92)90543-s

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Article

The mcm2 mutation of yeast affects replication, rather than segregation or amplification of the two micron plasmid.

Journal of molecular biology - 5 Apr 1992

Maiti A K, Sinha P

Abstract excerpt

We have studied the maintenance of the endogenous two micron (2 mu) plasmid in a strain of yeast carrying the nuclear mutation mcm2. This mutation, earlier shown to affect the maintenance of yeast minichromosomes in an ARS-dependent manner, also affected the copy number of the 2 mu plasmid. The e...

Topics

Cell Division
Chromosomes, Fungal
Cloning, Molecular
DNA Replication
DNA, Fungal
Gene Amplification
Mutation
Plasmids
Probability
Recombination, Genetic
Replicon
Saccharomyces cerevisiae
Temperature

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