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Article

The mcm2 mutation of yeast affects replication, rather than segregation or amplification of the two micron plasmid.

Journal of molecular biology - 5 Apr 1992

Maiti A K, Sinha P

Abstract excerpt

We have studied the maintenance of the endogenous two micron (2 mu) plasmid in a strain of yeast carrying the nuclear mutation mcm2. This mutation, earlier shown to affect the maintenance of yeast minichromosomes in an ARS-dependent manner, also affected the copy number of the 2 mu plasmid. The effect was more pronounced at 35 degrees C leading to the elimination of the plasmid from the cells cultured at this...

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Source

Identifiers

PMID: 1569546
DOI: 10.1016/0022-2836(92)90543-s

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The mcm2 mutation of yeast affects replication, rather than segregation or amplification of the two micron plasmid.PMID 1569546Read ↗

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