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[Stable maintenance of dicentric mini-chromosomes in CHL4 mutants in yeast].

Molekuliarnaia biologiia - 1 Jan 2000

Kuprina N Iu, Krol' E S, Koriabin M Iu, Bannikov V M, Kirillov A V, Zakhar'ev V M, Larionov V L

Abstract excerpt

Earlier we have identified the chl4-1 mutation in a screen for yeast mutants with increased loss of chromosome III and circular artificial minichromosome in mitosis. Mutation in the CHL4 gene leads to a 50-100-fold promotion in the rate of chromosome loss per cell division compared to the isogenic wild type strain. Detailed analysis of behaviour of the circular minichromosome marked by the CUP1 gene has shown...

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PMID: 8316241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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