Article
Pas1 is a common lung cancer susceptibility locus in three mouse strains.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1997
Manenti G, Gariboldi M, Fiorino A, Zedda A I, Pierotti M A, Dragani T A
Abstract excerpt
Inherited predisposition to lung cancer is a phenotypic trait shared by different mouse inbred strains that show either a high or an intermediate predisposition. Other strains are instead genetically resistant. The Pas1 locus is the major determinant of lung cancer predisposition in the A/J strain (Gariboldi et al. 1993). To define the determinants of susceptibility to lung tumorigenesis in the highly susceptible...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
