Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protein C and protein S in homozygous sickle cell disease: does hepatic dysfunction contribute to low levels?

British journal of haematology - 1 Sept 1997

Wright J G, Malia R, Cooper P, Thomas P, Preston F E, Serjeant G R

Abstract excerpt

The aim of this study was to confirm reports of low protein C (PC) and S (PS) concentrations in steady-state patients with homozygous sickle cell (SS) disease when compared to a racially matched normal haemoglobin (AA) control group and to examine the mechanisms of this reduction with respect to hepatic function, coagulation activation and haematological indices. In 36 SS patients and 35 AA race-matched controls...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Sickle Cell
Share to Factor V
Share to Factor VII

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Hemoglobins

Share to Liver Diseases

Share to Longitudinal Studies

Share to Protein C Deficiency

Source

Identifiers

PMID: 9332318
DOI: 10.1046/j.1365-2141.1997.2663083.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protein C and protein S in homozygous sickle cell disease: does hepatic dysfunction contribute to low levels?PMID 9332318Read ↗

Protein S deficiency.Semantic proximity Read ↗

Protein S abnormalities: A diagnostic nightmareSemantic proximity Read ↗

Protein S deficiency: a clinical perspective.Semantic proximity Read ↗

Protein C and protein S deficiencies: similarities and differences between two brothers playing in the same game.Semantic proximity Read ↗

Protein S.Semantic proximity Read ↗

Molecular basis of protein S deficiency.Semantic proximity Read ↗

Hereditary and acquired protein S deficiencies are associated with low TFPI levels in plasma.Semantic proximity Read ↗

A review of mutations causing deficiencies of antithrombin, protein C and protein S.Semantic proximity Read ↗

Protein S Gla-domain mutations causing impaired Ca(2+)-induced phospholipid binding and severe functional protein S deficiency.Semantic proximity Read ↗

Association of protein S p.Pro667Pro dimorphism with plasma protein S levels in normal individuals and patients with inherited protein S deficiency.Semantic proximity Read ↗

Genetic and phenotypic variability between families with hereditary protein S deficiency.Semantic proximity Read ↗

Normal functional protein S activity does not exclude protein S deficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.