Article
Molecular basis of protein S deficiency.
Thrombosis and haemostasis - 1 Sept 2007
García de Frutos Pablo, Fuentes-Prior Pablo, Hurtado Begoña, Sala Núria
Abstract excerpt
Protein S deficiency (PSD) has been the most difficult to study among the classical inherited thrombophilic factors. This is in part due to the peculiar biology of protein S (PS), which has an anticoagulant role but no enzymatic activity, and because it interacts with plasma components that function in both haemostasis and inflammation. Clinically, it also has been difficult to define and standardise valuable...
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