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Article

Association of protein S p.Pro667Pro dimorphism with plasma protein S levels in normal individuals and patients with inherited protein S deficiency.

Thrombosis research - 1 Jan 2007

Castaman G, Biguzzi E, Razzari C, Tosetto A, Fontana G, Asti D, Brancaccio V, Castori D, Lane D A, Faioni E M

Abstract excerpt

A dimorphism in PROS1 gene (c.A2,001G, p.Pro667Pro) has been associated with significantly reduced levels of both free and total protein S in carriers of the GG genotype. It is not known how the GG genotype could influence PS levels in normals, whether it could influence the levels of protein S in carriers of mutations in PROS1 gene and whether this genotype acts as an isolated or additive risk factor for venous...

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Identifiers

PMID: 17157360
DOI: 10.1016/j.thromres.2006.10.014

Genes

PROS1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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