Article
Protein S deficiency: a clinical perspective.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Nov 2008
ten Kate M K, van der Meer J
Abstract excerpt
Protein S (PS) is an extensively studied protein with an important function in the down-regulation of thrombin generation. Because of the presence of a pseudogene and two different forms of PS in plasma, a bound and a free form, it is one of the most difficult thrombophilias to study. A deficiency of PS predisposes subjects to (recurrent) venous thromboembolism (VTE) and foetal loss. However, the conundrum of...
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