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Article

Protein C and protein S deficiencies: similarities and differences between two brothers playing in the same game.

Clinical chemistry and laboratory medicine - 1 Dec 2010

Bereczky Zsuzsanna, Kovács Kitti B, Muszbek László

Abstract excerpt

Protein C (PC) and protein S (PS) are vitamin K-dependent glycoproteins that play an important role in the regulation of blood coagulation as natural anticoagulants. PC is activated by thrombin and the resulting activated PC (APC) inactivates membrane-bound activated factor VIII and factor V. The free form of PS is an important cofactor of APC. Deficiencies in these proteins lead to an increased risk of venous...

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PMID: 21054189
DOI: 10.1515/CCLM.2010.369

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APC

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Source receipt: pubmed, retrieved 7 Sept 2026.

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