Article
Analyses of the APC and TGF-beta type II receptor genes, and microsatellite instability in mucosal colorectal carcinomas.
Japanese journal of cancer research : Gann - 1 Aug 1997
Yagi O K, Akiyama Y, Ohkura Y, Ban S, Endo M, Saitoh K, Yuasa Y
Abstract excerpt
APC and transforming growth factor-beta type II receptor (TGF-beta RII) gene mutations, and microsatellite instability have been found in sporadic colorectal carcinomas. To clarify further the early alterations in colorectal carcinogenesis, we investigated these genetic changes in 23 protruding- and 24 superficial-type mucosal colorectal carcinomas. TGF-beta RII gene mutations and microsatellite instability were...
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