Article
Microsatellite instability is associated with the macroscopic configuration of neoplasms in patients with multiple colorectal adenomas.
Japanese journal of clinical oncology - 1 Jul 1998
Sasaki S, Masaki T, Umetani N, Shinozaki M, Yokoyama T, Ono M, Nagawa H, Muto T
Abstract excerpt
BACKGROUND: The management of patients with multiple colorectal adenomas, 10-100 in number, is often troublesome clinically. To establish the reasonable management of such cases, genetic backgrounds should be made clear. METHODS: For a total of 19 adenomas and four carcinomas from four patients w...
Topics
- Adenoma
- Adenomatous Polyposis Coli
- Base Sequence
- Carcinoma
- Colonic Neoplasms
- Female
- Genes, APC
- Humans
- Male
- Microsatellite Repeats
- Middle Aged
- Mutation
- Phenotype
- Rectal Neoplasms