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Article

Distortion of allelic expression of apolipoprotein E in Alzheimer's disease.

Human molecular genetics - 1 Nov 1997

Lambert J C, Pérez-Tur J, Dupire M J, Galasko D, Mann D, Amouyel P, Hardy J, Delacourte A, Chartier-Harlin M C

Abstract excerpt

The APOE epsilon4 allele is a strong genetic susceptibility factor for Alzheimer's disease. Interaction with other biological factors may modulate the effect of the apoE isoforms. However, previous work suggested that other genetic variability within the APOE locus, influencing the effect of the epsilon4 allele, may exist. Such variability could modify the expression of the APOE gene and, in particular, the level...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9328480
DOI: 10.1093/hmg/6.12.2151

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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