Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg.

doi:10.1111/j.1749-6632.1998.tb10653.x

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Article

Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg.

Annals of the New York Academy of Sciences - 30 Nov 1998

Roses A D

Abstract excerpt

Apolipoprotein E (APOE) is a true susceptibility polymorphism of the common form of Alzheimer's disease (AD). There are three APOE alleles (epsilon 2, epsilon 3, epsilon 4) that are universally distributed in the population with some variation in allele frequency due to racial and ethnic differen...

Topics

Alleles
Alzheimer Disease
Animals
Apolipoproteins E
Brain
Disease Models, Animal
Humans
Mice
Mice, Transgenic

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