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Article

Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg.

Annals of the New York Academy of Sciences - 30 Nov 1998

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Abstract excerpt

Apolipoprotein E (APOE) is a true susceptibility polymorphism of the common form of Alzheimer's disease (AD). There are three APOE alleles (epsilon 2, epsilon 3, epsilon 4) that are universally distributed in the population with some variation in allele frequency due to racial and ethnic differences, and are associated with different risks and age of onset distributions. In multiple studies, the positive...

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Source

Identifiers

PMID: 9929679
DOI: 10.1111/j.1749-6632.1998.tb10653.x

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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