Article
Drosophila CBP is required for dorsal-dependent twist gene expression.
Nature genetics - 1 Oct 1997
Akimaru H, Hou D X, Ishii S
Abstract excerpt
Although CREB-binding protein (CBP) functions as a co-activator of many transcription factors, relatively little is known about the physiological role of CBP. Mutations in the human CBP gene are associated with Rubinstein-Taybi syndrome, a haplo-insufficiency disorder characterized by abnormal pattern formation. Recently, we isolated a Drosophila CBP (dCBP) mutant, and found dCBP to be maternally expressed,...
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