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Article

Drosophila DOCK family protein sponge regulates the JNK pathway during thorax development.

Cell structure and function - 1 Jan 2014

Morishita Kazushige, Ozasa Fumito, Eguchi Koichi, Yoshioka Yasuhide, Yoshida Hideki, Hiai Hiroshi, Yamaguchi Masamitsu

Abstract excerpt

The dedicator of cytokinesis (DOCK) family proteins that are conserved in a wide variety of species are known as DOCK1-DOCK11 in mammals. The Sponge (Spg) is a Drosophila counterpart to the mammalian DOCK3. Specific knockdown of spg by pannir-GAL4 or apterous-GAL4 driver in wing discs induced split thorax phenotype in adults. Reduction of the Drosophila c-Jun N-terminal kinase (JNK), basket (bsk) gene dose...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25311449
DOI: 10.1247/csf.14008

Genes

DOCK1
DOCK11
DOCK3

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