Article
Patterns of gene expression during Drosophila mesoderm development.
Science (New York, N.Y.) - 31 Aug 2001
Furlong E E, Andersen E C, Null B, White K P, Scott M P
Abstract excerpt
The transcription factor Twist initiates Drosophila mesoderm development, resulting in the formation of heart, somatic muscle, and other cell types. Using a Drosophila embryo sorter, we isolated enough homozygous twist mutant embryos to perform DNA microarray experiments. Transcription profiles of twist loss-of-function embryos, embryos with ubiquitous twist expression, and wild-type embryos were compared at...
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