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Article

Discrete levels of Twist activity are required to direct distinct cell functions during gastrulation and somatic myogenesis.

PloS one - 1 Jan 2014

Wong Ming-Ching, Dobi Krista C, Baylies Mary K

Abstract excerpt

Twist (Twi), a conserved basic helix-loop-helix transcriptional regulator, directs the epithelial-to-mesenchymal transition (EMT), and regulates changes in cell fate, cell polarity, cell division and cell migration in organisms from flies to humans. Analogous to its role in EMT, Twist has been implicated in metastasis in numerous cancer types, including breast, pancreatic and prostate. In the Drosophila embryo,...

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Source

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Identifiers

PMID: 24915423
DOI: 10.1371/journal.pone.0099553
PMCID: PMC4051702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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