Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae.

doi:10.1128/MCB.17.10.6105

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Article

Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Oct 1997

Huang M, Elledge S J

Abstract excerpt

Ribonucleotide reductase (RNR), which catalyzes the rate-limiting step for deoxyribonucleotide production required for DNA synthesis, is an alpha2beta2 tetramer consisting of two large and two small subunits. RNR2 encodes a small subunit and is essential for mitotic viability in Saccharomyces cer...

Topics

Amino Acid Sequence
Cell Cycle Proteins
Checkpoint Kinase 2
Cloning, Molecular
DNA Damage
DNA Replication
DNA, Fungal
Fungal Proteins
Gene Expression Regulation, Fungal
Genes, Fungal
Genetic Complementation Test
Intracellular Signaling Peptides and Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Protein Kinases

Protein Serine-Threonine Kinases

RNA, Fungal

RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 9315670
DOI: 10.1128/MCB.17.10.6105
PMCID: PMC232460

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9315670-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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