Article
Rnr4p, a novel ribonucleotide reductase small-subunit protein.
Molecular and cellular biology - 1 Oct 1997
Wang P J, Chabes A, Casagrande R, Tian X C, Thelander L, Huffaker T C
Abstract excerpt
Ribonucleotide reductases catalyze the formation of deoxyribonucleotides by the reduction of the corresponding ribonucleotides. Eukaryotic ribonucleotide reductases are alpha2beta2 tetramers; each of the larger, alpha subunits possesses binding sites for substrate and allosteric effectors, and each of the smaller, beta subunits contains a binuclear iron complex. The iron complex interacts with a specific tyrosine...
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