Article
Drosophila melanogaster deficient in protein kinase A manifests behavior-specific arrhythmia but normal clock function.
Molecular and cellular biology - 1 Oct 1997
Majercak J, Kalderon D, Edery I
Abstract excerpt
Drosophila melanogaster bearing mutations in the DCO gene, which encodes the major catalytic subunit of cAMP-dependent protein kinase (PKA), displays arrhythmic locomotor activity strongly suggesting a role for PKA in the circadian timing system. This arrhythmicity might result from a requirement...
Topics
- Animals
- Behavior, Animal
- Biological Clocks
- Circadian Rhythm
- Cyclic AMP-Dependent Protein Kinases
- Drosophila Proteins
- Drosophila melanogaster
- Homozygote
- Larva
- Male
- Motor Activity
- Mutation
- Nuclear Proteins
- Period Circadian Proteins
- RNA, Messenger