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Article

Phosphorylation of a central clock transcription factor is required for thermal but not photic entrainment.

PLoS genetics - 1 Aug 2014

Lee Euna, Jeong Eun Hee, Jeong Hyun-Jeong, Yildirim Evrim, Vanselow Jens T, Ng Fanny, Liu Yixiao, Mahesh Guruswamy, Kramer Achim, Hardin Paul E, Edery Isaac, Kim Eun Young

Abstract excerpt

Transcriptional/translational feedback loops drive daily cycles of expression in clock genes and clock-controlled genes, which ultimately underlie many of the overt circadian rhythms manifested by organisms. Moreover, phosphorylation of clock proteins plays crucial roles in the temporal regulation of clock protein activity, stability and subcellular localization. dCLOCK (dCLK), the master transcription factor...

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PMID: 25121504
DOI: 10.1371/journal.pgen.1004545
PMCID: PMC4133166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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