Article
Localization and functions of protein kinase A during Drosophila oogenesis.
Mechanisms of development - 1 Feb 1995
Lane M E, Kalderon D
Abstract excerpt
We have characterized the requirements for the Protein Kinase A (PKA) catalytic subunit, DC0, in Drosophila oogenesis. Intercellular bridges in egg chambers from PKA deficient females are unstable, leading to the formation of multinucleate nurse cells by fusions of adjacent cells. Germline clones of cells homozygous for null mutations of DC0 indicate that PKA acts autonomously in the germline. Highest levels of...
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