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Article

Molecular basis of esophageal cancer development and progression.

The Surgical clinics of North America - 1 Oct 2012

Denlinger Chadrick E, Thompson Robert K

Abstract excerpt

This article discusses the molecular basis of esophageal cancer development and subsequent progression of disease. Differing epidemiologic factors are associated with esophageal adenocarcinoma and squamous cell carcinoma. These 2 different histologic types have differing putative underlying mechanisms of transdifferentiation from normal esophageal mucosa to malignant histologies via gene dysregulation,...

Topics

Adenocarcinoma
Alcohol Drinking
Barrett Esophagus
Biomarkers
Carcinoma, Squamous Cell
Cell Transformation, Neoplastic
Esophageal Neoplasms
Gene Expression Regulation, Neoplastic
Genetic Markers
Humans
Molecular Targeted Therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Smoking

Source

Identifiers

PMID: 23026271
DOI: 10.1016/j.suc.2012.07.002

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