Article
The molecular biology of esophageal and gastric cancer and their precursors: oncogenes, tumor suppressor genes, and growth factors.
Human pathology - 1 Oct 1994
Stemmermann G, Heffelfinger S C, Noffsinger A, Hui Y Z, Miller M A, Fenoglio-Preiser C M
Abstract excerpt
The evolution of sequential histological changes from normal cells through invasive cancer affords the cancer biologist the opportunity to identify separate molecular steps involved in cancer progression. As one studies the development of human carcinoma, it becomes apparent that multiple genetic alterations affecting both cellular proto-oncogenes and tumor suppressor genes are involved during the development and...
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