Article
Genetic alterations in esophageal cancer.
Surgery today - 1 Jan 2005
Kuwano Hiroyuki, Kato Hiroyuki, Miyazaki Tatsuya, Fukuchi Minoru, Masuda Norihiro, Nakajima Masanobu, Fukai Yasuyuki, Sohda Makoto, Kimura Hitoshi, Faried Ahmad
Abstract excerpt
Esophageal cancer is a common malignancy with a striking variation in geographical distribution; a reflection of exposure to specific environmental factors, which are still poorly defined. We discuss the recent progress made in the investigation of the molecular biology of esophageal cancer, addressing the topics of genetic alterations, methylation, overexpression of molecules thought to cause malignant...
Topics
- Carcinoma, Squamous Cell
- Cell Transformation, Neoplastic
- ErbB Receptors
- Esophageal Neoplasms
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Incidence
- Japan
- Male
- Molecular Biology
- Mutation
- Neoplasm Staging
- Prognosis
