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Article

Genomic gains and losses in malignant mesothelioma demonstrated by FISH analysis of paraffin-embedded tissues.

Journal of clinical pathology - 1 Jan 2012

Takeda Maiko, Kasai Takahiko, Enomoto Yasunori, Takano Masato, Morita Kouhei, Kadota Eiji, Iizuka Norishige, Maruyama Hiroshi, Nonomura Akitaka

Abstract excerpt

AIMS: Malignant mesothelioma (MM) results from the accumulation of a number of acquired genetic events at the onset. In MM, the most frequent changes were losses in 9p21, 1p36, 14q32 and 22q12, and gains in 5p, 7p and 8q24 by comparative genomic hybridisation analysis. Although the diagnostic utility of 9p21 homozygous deletion by fluorescence in situ hybridisation (FISH) analysis in MM has been reported...

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Share to Chromosomes, Human
Share to Comparative Genomic Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

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Share to Neoplasm Staging

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Source

Identifiers

PMID: 22081786
DOI: 10.1136/jclinpath-2011-200208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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