Article
Effects of apolipoprotein E on dementia and aging in the Shanghai Survey of Dementia.
Neurology - 1 Sept 1997
Katzman R, Zhang M Y, Chen P J, Gu N, Jiang S, Saitoh T, Chen X, Klauber M, Thomas R G, Liu W T, Yu E S
Abstract excerpt
We investigated the status of the apolipoprotein E allele in 538 participants in the incidence phase of the ongoing Shanghai Survey of Dementia, including 103 demented subjects, 72 with mild cognitive impairment and 363 cognitively normal. The apo E epsilon 4 allele was present in 10.2% of control subjects and the allelic frequency did not change between ages 60 to 96 years. The apo E epsilon 4 allelic frequency...
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