Article
Polymorphism of gamma-adducin gene in genetic hypertension and mapping of the gene to rat chromosome 1q55.
Biochemical and biophysical research communications - 28 Aug 1997
Tripodi G, Szpirer C, Reina C, Szpirer J, Bianchi G
Abstract excerpt
Adducin (ADD) is a heterodimeric protein involved in cellular signal transduction. A mutation in the alpha subunit affects ion transport and blood pressure in primary hypertension of Milan rats (MHS) and humans. In rats this effect is modulated by another mutation in the beta subunit. The recently described gamma subunit is a new member of the ADD family that should take the place of beta subunit in cells and...
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