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Article

Association of the alpha-adducin locus with essential hypertension.

Hypertension (Dallas, Tex. : 1979) - 1 Mar 1995

Casari G, Barlassina C, Cusi D, Zagato L, Muirhead R, Righetti M, Nembri P, Amar K, Gatti M, Macciardi F

Abstract excerpt

Previous studies on genetic rat hypertension have shown that polymorphism within the alpha-adducin gene may regulate blood pressure. Adducin is a cytoskeletal protein that may be involved in cellular signal transduction and interacts with other membrane-skeleton proteins that affect ion transport across the cell membrane. There is a high homology between rat and human adducin and pathophysiological similarities...

Topics

Aged
Aging
Alleles
Blood Proteins
Body Mass Index
Calmodulin-Binding Proteins
Chromosome Mapping
Female
Genotype
Humans
Hypertension
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Multigene Family

Sex Characteristics

Source

Identifiers

PMID: 7875756
DOI: 10.1161/01.hyp.25.3.320

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7875756-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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