Article
Characterisation and chromosomal localisation of the rat alpha- and beta-adducin-encoding genes.
Gene - 12 Dec 1995
Tripodi G, Casari G, Tisminetzky S, Bianchi G, Devescovi G, Muro A, Tuteja R, Baralle F E
Abstract excerpt
A polymorphism in the genes encoding alpha- and beta-adducin (ADD) was described as being associated with blood-pressure variation in a genetically hypertensive strain of rats (MHS). ADD is a cytoskeletal heterodimeric protein which may be involved in cellular signal transduction and interacts with other membrane skeleton proteins which affect ion transport across the cell membrane. The cDNA encoding the alpha...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.